Understanding the differences between connective tissue disorders is critical when facing surgery, because these conditions can significantly affect how the body responds to anesthesia, heals wounds, and recovers from trauma. For example, patients with Ehlers-Danlos Syndrome may have fragile tissues, delayed healing, or increased bleeding risks, while those with vascular EDS face even more serious complications due to the fragility of blood vessels. Not all connective tissue disorders affect the body in the same way, so it’s essential that surgeons, anesthesiologists, and care teams know the specific diagnosis and tailor their approach accordingly. Proper pre-op planning, surgical technique modifications, and post-op care can make a major difference in outcomes—and help avoid preventable complication